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Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity
BACKGROUND: Elevated glucocorticoid production and reduced hypothalamic POMC mRNA can cause obese phenotypes. Conversely, adrenalectomy can reverse obese phenotypes caused by the absence of leptin, a model in which glucocorticoid production is elevated. Adrenalectomy also increases hypothalamic POMC...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165436/ https://ncbi.nlm.nih.gov/pubmed/12795810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-3-4 |
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