Glucagon-Like Peptide 1 Stimulates Hypothalamic Proopiomelanocortin Neurons

Glucagon-like peptide 1 (GLP-1) is a potent inhibitor of food intake. GLP-1 receptor mRNA is densely expressed in hypothalamic arcuate nucleus (ARC) and precisely overlaps the area occupied by proopiomelanocortin (POMC) neurons. Activation of POMC neurons suppresses appetite, and lack of POMC-derive...

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Bibliographic Details
Main Authors: Ma, Xiaosong, Bruning, Jens, Ashcroft, Frances M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2007
Subjects:
Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868967/
https://ncbi.nlm.nih.gov/pubmed/17611265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1025-07.2007
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