Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.

To examine the influence of the putative satiety factor (GLP-1) on the hypothalamo-pituitary-gonadal axis, we used GT1-7 cells as a model of neuronal luteinizing hormone- releasing hormone (LHRH) release. GLP-1 caused a concentration-dependent increase in LHRH release from GT1-7 cells. Specific, sat...

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Bibliographic Details
Main Authors: Beak, S A, Heath, M M, Small, C J, Morgan, D G, Ghatei, M A, Taylor, A D, Buckingham, J C, Bloom, S R, Smith, D M
Format: Artigo
Language:Inglês
Published: 1998
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508688/
https://ncbi.nlm.nih.gov/pubmed/9502775
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