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Molecular Distinction between Pathogenic and Infectious Properties of the Prion Protein
Tg(PG14) mice express a prion protein (PrP) with a nine-octapeptide insertion associated with a human familial prion disease. These animals spontaneously develop a fatal neurodegenerative disorder characterized by ataxia, neuronal apoptosis, and accumulation in the brain of an aggregated and weakly...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2003
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164780/ https://ncbi.nlm.nih.gov/pubmed/12805461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7611-7622.2003 |
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