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Protein dynamics and catalysis: the problems of transition state theory and the subtlety of dynamic control

This manuscript describes ongoing research on the nature of chemical reactions in enzymes. We will investigate how protein dynamics can couple to chemical reaction in an enzyme. We first investigate in some detail why transition state theory cannot fully describe the dynamics of chemical reactions c...

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Detalhes bibliográficos
Main Authors: Pineda, J.R.E.T, Schwartz, S.D
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1647311/
https://ncbi.nlm.nih.gov/pubmed/16873129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2006.1877
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