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Transition state theory can be used in studies of enzyme catalysis: lessons from simulations of tunnelling and dynamical effects in lipoxygenase and other systems

The idea that enzyme catalysis involves special factors such as coherent fluctuations, quantum mechanical tunnelling and non-equilibrium solvation (NES) effects has gained popularity in recent years. It has also been suggested that transition state theory (TST) cannot be used in studies of enzyme ca...

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Detalhes bibliográficos
Main Authors: Olsson, Mats H.M, Mavri, Janez, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1647313/
https://ncbi.nlm.nih.gov/pubmed/16873128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2006.1880
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