טוען...
Simulating the Fidelity And The Three Mg Mechanism of Pol η and clarifying the validity of transition state theory in enzyme catalysis
Pol η belongs to the important Y family of DNA polymerases that can catalyze translesion synthesis across sites of damaged DNA. This activity involves the reduced fidelity of Pol η for 8-oxo-7,8-dhyedro-2′-deoxoguanosin(8-oxoG). The fundamental interest in Pol η has grown recently with the demonstra...
שמור ב:
| הוצא לאור ב: | Proteins |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531179/ https://ncbi.nlm.nih.gov/pubmed/28383109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25305 |
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