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Quantifying the limits of transition state theory in enzymatic catalysis

While being one of the most popular reaction rate theories, the applicability of transition state theory to the study of enzymatic reactions has been often challenged. The complex dynamic nature of the protein environment raised the question about the validity of the nonrecrossing hypothesis, a corn...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Zinovjev, Kirill, Tuñón, Iñaki
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703300/
https://ncbi.nlm.nih.gov/pubmed/29101125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710820114
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