Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero

In animals, including humans, the source of long-chain saturated fatty acids is de novo synthesis, which is mediated by fatty acid synthase (FAS), ingested food, or both. To understand the importance of de novo fatty acid synthesis, we generated FAS knockout mice. The heterozygous FAS mutants (Fasn(...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Chirala, Subrahmanyam S., Chang, Hua, Matzuk, Martin, Abu-Elheiga, Lutfi, Mao, Jianqiang, Mahon, Kathleen, Finegold, Milton, Wakil, Salih J.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 2003
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12738878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0931394100
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!