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Possible Therapeutic Vaccine Strategy against Human Immunodeficiency Virus Escape from Reverse Transcriptase Inhibitors Studied in HLA-A2 Transgenic Mice

Mutation of human immunodeficiency virus (HIV) leading to escape from anti-HIV drugs is the greatest challenge to the treatment of HIV infection. High-grade resistance to the nucleoside reverse transcriptase (RT) inhibitor lamivudine (also known as 3TC) is associated with a substitution of valine fo...

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Библиографические подробности
Главные авторы: Okazaki, Takahiro, Terabe, Masaki, Catanzaro, Andrew T., Pendleton, C. David, Yarchoan, Robert, Berzofsky, Jay A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641790/
https://ncbi.nlm.nih.gov/pubmed/16920824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01351-05
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