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Potent antifungal effects of a new derivative of partricin A in a murine model of cerebral cryptococcosis.

A new member of the polyene family, N-dimethylaminoacetyl-partricin A 2-dimethylaminoethylamide diaspartate (SPA), was investigated and was found to be more effective than amphotericin B (i) in vivo by enhancing mouse resistance to cryptococcal meningoencephalitis and (ii) in vitro by potentiating t...

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Detalhes bibliográficos
Main Authors: Luna, T, Mazzolla, R, Romanò, G, Blasi, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163777/
https://ncbi.nlm.nih.gov/pubmed/9056019
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