Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Potent Antifungal Agents

With the goal of obtaining a novel bioactive compound with significant antifungal activity, a series of 1,3,4-thiadiazole derivatives (3a–3l) were synthesized and characterized. Due to thione-thiol tautomerism in the intermediate compound 2, type of substitution reaction in the final step was determ...

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Gepubliceerd in:Molecules
Hoofdauteurs: Karaburun, Ahmet Çağrı, Acar Çevik, Ulviye, Osmaniye, Derya, Sağlık, Begüm Nurpelin, Kaya Çavuşoğlu, Betül, Levent, Serkan, Özkay, Yusuf, Koparal, Ali Savaş, Behçet, Mustafa, Kaplancıklı, Zafer Asım
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6321371/
https://ncbi.nlm.nih.gov/pubmed/30501053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23123129
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