Llwytho...

Novel 1,3,4-thiadiazole compounds as potential MAO-A inhibitors – design, synthesis, biological evaluation and molecular modelling

Monoamine oxidases (MAOs) are important drug targets for the management of neurological disorders. Herein, a series of new 1,3,4-thiadiazole derivatives bearing various alkyl/arylamine moieties as MAO inhibitors were designed and synthesized. All of the compounds were more selective against hMAO-A t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RSC Med Chem
Prif Awduron: Sağlık, Begüm Nurpelin, Kaya Çavuşoğlu, Betül, Acar Çevik, Ulviye, Osmaniye, Derya, Levent, Serkan, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7513386/
https://ncbi.nlm.nih.gov/pubmed/33479699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00150c
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!