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Hormonal Control of Androgen Receptor Function through SIRT1
The NAD-dependent histone deacetylase Sir2 plays a key role in connecting cellular metabolism with gene silencing and aging. The androgen receptor (AR) is a ligand-regulated modular nuclear receptor governing prostate cancer cellular proliferation, differentiation, and apoptosis in response to andro...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636736/ https://ncbi.nlm.nih.gov/pubmed/16923962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00289-06 |
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