Hormonal Control of Androgen Receptor Function through SIRT1

The NAD-dependent histone deacetylase Sir2 plays a key role in connecting cellular metabolism with gene silencing and aging. The androgen receptor (AR) is a ligand-regulated modular nuclear receptor governing prostate cancer cellular proliferation, differentiation, and apoptosis in response to andro...

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Autors principals: Fu, Maofu, Liu, Manran, Sauve, Anthony A., Jiao, Xuanmao, Zhang, Xueping, Wu, Xiaofang, Powell, Michael J., Yang, Tianle, Gu, Wei, Avantaggiati, Maria Laura, Pattabiraman, Nagarajan, Pestell, Timothy G., Wang, Fang, Quong, Andrew A., Wang, Chenguang, Pestell, Richard G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636736/
https://ncbi.nlm.nih.gov/pubmed/16923962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00289-06
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