Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth

Modification by acetylation occurs at ɛ-amino lysine residues of histones and transcription factors. Unlike phosphorylation, a direct link between transcription factor acetylation and cellular growth or apoptosis has not been established. We show that the nuclear androgen receptor (AR), a DNA-bindin...

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Hlavní autoři: Fu, Maofu, Rao, Mahadev, Wang, Chenguang, Sakamaki, Toshiyuki, Wang, Jian, Di Vizio, Dolores, Zhang, Xueping, Albanese, Chris, Balk, Steven, Chang, Chawnshang, Fan, Saijun, Rosen, Eliot, Palvimo, Jorma J., Jänne, Olli A., Muratoglu, Selen, Avantaggiati, Maria Laura, Pestell, Richard G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC262657/
https://ncbi.nlm.nih.gov/pubmed/14612401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8563-8575.2003
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