TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy

Angiotensin (Ang) II participates in the pathogenesis of heart failure through induction of cardiac hypertrophy. Ang II-induced hypertrophic growth of cardiomyocytes is mediated by nuclear factor of activated T cells (NFAT), a Ca(2+)-responsive transcriptional factor. It is believed that phospholipa...

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Hlavní autoři: Onohara, Naoya, Nishida, Motohiro, Inoue, Ryuji, Kobayashi, Hiroyuki, Sumimoto, Hideki, Sato, Yoji, Mori, Yasuo, Nagao, Taku, Kurose, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636614/
https://ncbi.nlm.nih.gov/pubmed/17082763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601417
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