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Heterotrimeric G Protein Gα13-Induced Induction of Cytokine mRNAs Through Two Distinct Pathways in Cardiac Fibroblasts

Abstract.: Overexpression of constitutively active (CA)-Gα13 significantly increased the expression of interleukin (IL)-1β and IL-6 mRNAs and proteins in rat cardiac fibroblasts. IL-1β mRNA induction by CA-Gα13 was suppressed by diphenyleneiodonium (DPI), an NADPH oxidase inhibitor, but not by BAPTA...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nagamatsu Yuichi, Nishida Motohiro, Onohara Naoya, Fukutomi Masashi, Maruyama Yoshiko, Kobayashi Hiroyuki, Sato Yoji, Kurose Hitoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2006-01-01
Cyfres:Journal of Pharmacological Sciences
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S1347861319344597
Tagiau: Ychwanegu Tag
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