Phosphorylation of TRPC6 Channels at Thr(69) Is Required for Anti-hypertrophic Effects of Phosphodiesterase 5 Inhibition

Activation of Ca(2+) signaling induced by receptor stimulation and mechanical stress plays a critical role in the development of cardiac hypertrophy. A canonical transient receptor potential protein subfamily member, TRPC6, which is activated by diacylglycerol and mechanical stretch, works as an ups...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nishida, Motohiro, Watanabe, Kenta, Sato, Yoji, Nakaya, Michio, Kitajima, Naoyuki, Ide, Tomomi, Inoue, Ryuji, Kurose, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857061/
https://ncbi.nlm.nih.gov/pubmed/20177073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074104
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados