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A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrand crosslinks

DNA interstrand crosslinks (ICLs) are highly cytotoxic lesions formed by a variety of important anti-tumor agents. Despite the clinical importance of ICLs, the mechanisms by which these lesions are repaired in mammalian cells have so far remained elusive. One of the obstacles in the study of ICL rep...

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Bibliografski detalji
Glavni autori: Alzeer, Jawad, Schärer, Orlando D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636361/
https://ncbi.nlm.nih.gov/pubmed/16945959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl587
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