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Polypyrimidine Tract Binding Protein Blocks the 5′ Splice Site Dependent Assembly of U2AF and the Prespliceosomal E Complex

Polypyrimidine tract binding protein (PTB) represses the splicing of many alternatively spliced exons. This repression can sometimes involve the direct occlusion of splice sites by PTB. We show here that PTB prevents splicing of the c-src N1 exon to downstream exon 4 by a different mechanism. PTB do...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sharma, Shalini, Falick, Arnold M., Black, Douglas L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635971/
https://ncbi.nlm.nih.gov/pubmed/16109373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.07.014
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