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Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

Alternative splicing patterns are regulated by RNA binding proteins that assemble onto each pre-mRNA to form a complex RNP structure. The polypyrimidine tract binding protein, PTB, has served as an informative model for understanding how RNA binding proteins affect spliceosome assembly and how chang...

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Détails bibliographiques
Auteurs principaux: Keppetipola, Niroshika, Sharma, Shalini, Li, Qin, Black, Douglas L.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422667/
https://ncbi.nlm.nih.gov/pubmed/22655688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2012.691456
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