Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2

Most human genes generate multiple protein isoforms through alternative pre-mRNA splicing, but the mechanisms controlling alternative splicing choices by RNA binding proteins are not well understood. These proteins can have multiple paralogs expressed in different cell types and exhibiting different...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Keppetipola, Niroshika M., Yeom, Kyu-Hyeon, Hernandez, Adrian L., Bui, Tessa, Sharma, Shalini, Black, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931110/
https://ncbi.nlm.nih.gov/pubmed/27288314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057505.116
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