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Polypyrimidine Tract Binding Protein Blocks the 5′ Splice Site Dependent Assembly of U2AF and the Prespliceosomal E Complex

Polypyrimidine tract binding protein (PTB) represses the splicing of many alternatively spliced exons. This repression can sometimes involve the direct occlusion of splice sites by PTB. We show here that PTB prevents splicing of the c-src N1 exon to downstream exon 4 by a different mechanism. PTB do...

詳細記述

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書誌詳細
主要な著者: Sharma, Shalini, Falick, Arnold M., Black, Douglas L.
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635971/
https://ncbi.nlm.nih.gov/pubmed/16109373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2005.07.014
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