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Electrostatic Potential Energy within a Protein Monitored by Metal Charge-Dependent Hydrogen Exchange
Hydrogen exchange measurements on Zn(II)-, Ga(III)-, and Ge(IV)-substituted Pyrococcus furiosus rubredoxin demonstrate that the log ratio of the base-catalyzed rate constants (Δ log k(ex)) varies inversely with the distance out to at least 12 Å from the metal. This pattern is consistent with the var...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Biophysical Society
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635659/ https://ncbi.nlm.nih.gov/pubmed/17012322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.094219 |
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