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Electrostatic Potential Energy within a Protein Monitored by Metal Charge-Dependent Hydrogen Exchange

Hydrogen exchange measurements on Zn(II)-, Ga(III)-, and Ge(IV)-substituted Pyrococcus furiosus rubredoxin demonstrate that the log ratio of the base-catalyzed rate constants (Δ log k(ex)) varies inversely with the distance out to at least 12 Å from the metal. This pattern is consistent with the var...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Anderson, Janet S., LeMaster, David M., Hernández, Griselda
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Biophysical Society 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635659/
https://ncbi.nlm.nih.gov/pubmed/17012322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.094219
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