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Assessing the Native State Conformational Distribution of Ubiquitin by Peptide Acidity

At equilibrium, every energetically feasible conformation of a protein occurs with a non-zero probability. Quantitative analysis of protein flexibility is thus synonymous with determining the proper Boltzmann-weighting of this conformational distribution. The exchange reactivity of solvent-exposed a...

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Bibliografiska uppgifter
Huvudupphovsmän: Hernández, Griselda, Anderson, Janet S., LeMaster, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092376/
https://ncbi.nlm.nih.gov/pubmed/21055867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2010.10.006
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