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Peptide Conformer Acidity Analysis of Protein Flexibility Monitored by Hydrogen Exchange

[Image: see text] The amide hydrogens that are exposed to solvent in the high-resolution X-ray structures of ubiquitin, FK506-binding protein, chymotrypsin inhibitor 2, and rubredoxin span a billion-fold range in hydroxide-catalyzed exchange rates which are predictable by continuum dielectric method...

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Detalhes bibliográficos
Main Authors: LeMaster, David M., Anderson, Janet S., Hernández, Griselda
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2009
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754664/
https://ncbi.nlm.nih.gov/pubmed/19722680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901219x
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