Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents

Peptide deformylase (PDF) catalyzes the hydrolytic removal of the N-terminal formyl group from nascent proteins. This is an essential step in bacterial protein synthesis, making PDF an attractive target for antibacterial drug development. Essentiality of the def gene, encoding PDF from Mycobacterium...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Teo, Jeanette W. P., Thayalan, Pamela, Beer, David, Yap, Amelia S. L., Nanjundappa, Mahesh, Ngew, Xinyi, Duraiswamy, Jeyaraj, Liung, Sarah, Dartois, Veronique, Schreiber, Mark, Hasan, Samiul , Cynamon, Michael, Ryder, Neil S., Yang, Xia, Weidmann, Beat, Bracken, Kathryn , Dick, Thomas, Mukherjee, Kakoli
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Susceptibility
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635232/
https://ncbi.nlm.nih.gov/pubmed/16966397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00555-06
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