In Vivo Characterization of the Peptide Deformylase Inhibitor LBM415 in Murine Infection Models

LBM415 is an antibacterial agent belonging to the peptide deformylase inhibitor class of compounds. It has previously been shown to demonstrate good activity in vitro against a range of pathogens. In this study, the in vivo efficacy of LBM415 was evaluated in various mouse infection models. We inves...

Full description

Saved in:
Bibliographic Details
Main Authors: Osborne, Colin S., Neckermann, Georg, Fischer, Evelin, Pecanka, Robert, Yu, Donghui, Manni, Kari, Goldovitz, Julie, Amaral, Kerri, Dzink-Fox, JoAnn, Ryder, Neil S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737836/
https://ncbi.nlm.nih.gov/pubmed/19596876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00026-09
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items