In Vivo Characterization of the Peptide Deformylase Inhibitor LBM415 in Murine Infection Models

LBM415 is an antibacterial agent belonging to the peptide deformylase inhibitor class of compounds. It has previously been shown to demonstrate good activity in vitro against a range of pathogens. In this study, the in vivo efficacy of LBM415 was evaluated in various mouse infection models. We inves...

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Bibliographische Detailangaben
Hauptverfasser: Osborne, Colin S., Neckermann, Georg, Fischer, Evelin, Pecanka, Robert, Yu, Donghui, Manni, Kari, Goldovitz, Julie, Amaral, Kerri, Dzink-Fox, JoAnn, Ryder, Neil S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737836/
https://ncbi.nlm.nih.gov/pubmed/19596876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00026-09
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