Evaluation of LBM415 (NVP PDF-713), a Novel Peptide Deformylase Inhibitor, for Treatment of Experimental Mycoplasma pneumoniae Pneumonia

Mycoplasma pneumoniae is a major cause of community-acquired pneumonia. We evaluated the efficacy of LBM415, a novel peptide deformylase inhibitor antimicrobial agent, for the treatment of M. pneumoniae pneumonia in a mouse model. Eight-week-old BALB/c mice were intranasally inoculated once with 10(...

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Autores principales: Fonseca-Aten, Monica, Salvatore, Christine M., Mejías, Asunción, Ríos, Ana M., Chávez-Bueno, Susana, Katz, Kathy, Gómez, Ana M., McCracken, George H., Hardy, R. Doug
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251520/
https://ncbi.nlm.nih.gov/pubmed/16189089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4128-4136.2005
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