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In Vivo Characterization of the Peptide Deformylase Inhibitor LBM415 in Murine Infection Models

LBM415 is an antibacterial agent belonging to the peptide deformylase inhibitor class of compounds. It has previously been shown to demonstrate good activity in vitro against a range of pathogens. In this study, the in vivo efficacy of LBM415 was evaluated in various mouse infection models. We inves...

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Autors principals: Osborne, Colin S., Neckermann, Georg, Fischer, Evelin, Pecanka, Robert, Yu, Donghui, Manni, Kari, Goldovitz, Julie, Amaral, Kerri, Dzink-Fox, JoAnn, Ryder, Neil S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737836/
https://ncbi.nlm.nih.gov/pubmed/19596876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00026-09
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