Role of the AcrAB-TolC Efflux Pump in Determining Susceptibility of Haemophilus influenzae to the Novel Peptide Deformylase Inhibitor LBM415

Haemophilus influenzae isolates vary widely in their susceptibilities to the peptide deformylase inhibitor LBM415 (MIC range, 0.06 to 32 μg/ml); however, on average, they are less susceptible than gram-positive organisms, such as Staphylococcus aureus and Streptococcus pneumoniae. Insertional inacti...

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Autores principales: Dean, Charles R., Narayan, Shubha, Daigle, Denis M., Dzink-Fox, JoAnn L., Puyang, Xiaoling, Bracken, Kathryn R., Dean, Karl E., Weidmann, Beat, Yuan, Zhengyu, Jain, Rakesh, Ryder, Neil S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196275/
https://ncbi.nlm.nih.gov/pubmed/16048914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3129-3135.2005
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