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The Efflux Pump Inhibitor Timcodar Improves the Potency of Antimycobacterial Agents

Previous studies indicated that inhibition of efflux pumps augments tuberculosis therapy. In this study, we used timcodar (formerly VX-853) to determine if this efflux pump inhibitor could increase the potency of antituberculosis (anti-TB) drugs against Mycobacterium tuberculosis in in vitro and in...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Grossman, Trudy H., Shoen, Carolyn M., Jones, Steven M., Jones, Peter L., Cynamon, Michael H., Locher, Christopher P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325793/
https://ncbi.nlm.nih.gov/pubmed/25534740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04271-14
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