Sarothrin from Alkanna orientalis is an antimicrobial agent and efflux pump inhibitor

An Alkanna orientalis leaf and flower extract inhibited the growth of Staphylococcus aureus, a pathogen that causes an estimated 478,000 hospitalizations in the US annually. Bioassay-guided fractionation of A. orientalis resulted in isolation of the flavonoid sarothrin (5,7,4′-trihydroxy-3,6,8-trime...

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Bibliografiske detaljer
Udgivet i:Planta Med
Main Authors: Bame, Jessica R., Graf, Tyler N., Junio, Hiyas A., Bussey, R. Owen, Jarmusch, Scott A., El-Elimat, Tamam, Falkinham, Joseph O., Oberlies, Nicholas H., Cech, Richard A., Cech, Nadja B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527991/
https://ncbi.nlm.nih.gov/pubmed/23468310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1328259
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