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A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition

Bacterial efflux pumps are active transport proteins responsible for resistance to selected biocides and antibiotics. It has been shown that production of efflux pumps is up-regulated in a number of highly pathogenic bacteria, including methicillin resistant Staphylococcus aureus. Thus, the identifi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Brown, Adam R., Ettefagh, Keivan A., Todd, Daniel, Cole, Patrick S., Egan, Joseph M., Foil, Daniel H., Graf, Tyler N., Schindler, Bryan D., Kaatz, Glenn W., Cech, Nadja B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427306/
https://ncbi.nlm.nih.gov/pubmed/25961825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124814
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