A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition

Bacterial efflux pumps are active transport proteins responsible for resistance to selected biocides and antibiotics. It has been shown that production of efflux pumps is up-regulated in a number of highly pathogenic bacteria, including methicillin resistant Staphylococcus aureus. Thus, the identifi...

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Publicat a:PLoS One
Autors principals: Brown, Adam R., Ettefagh, Keivan A., Todd, Daniel, Cole, Patrick S., Egan, Joseph M., Foil, Daniel H., Graf, Tyler N., Schindler, Bryan D., Kaatz, Glenn W., Cech, Nadja B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427306/
https://ncbi.nlm.nih.gov/pubmed/25961825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124814
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