Multidrug efflux in intrinsic resistance to trimethoprim and sulfamethoxazole in Pseudomonas aeruginosa.

Pseudomonas aeruginosa possesses at least two multiple drug efflux systems which are defined by the outer membrane proteins OprM and OprJ. We have found that mutants overexpressing OprM were two- and eightfold more resistant than their wild-type parent to sulfamethoxazole (SMX) and trimethoprim (TMP...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Köhler, T, Kok, M, Michea-Hamzehpour, M, Plesiat, P, Gotoh, N, Nishino, T, Curty, L K, Pechere, J C
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1996
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9036831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2288
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