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Multidrug efflux in intrinsic resistance to trimethoprim and sulfamethoxazole in Pseudomonas aeruginosa.

Pseudomonas aeruginosa possesses at least two multiple drug efflux systems which are defined by the outer membrane proteins OprM and OprJ. We have found that mutants overexpressing OprM were two- and eightfold more resistant than their wild-type parent to sulfamethoxazole (SMX) and trimethoprim (TMP...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Köhler, T, Kok, M, Michea-Hamzehpour, M, Plesiat, P, Gotoh, N, Nishino, T, Curty, L K, Pechere, J C
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163521/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9036831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2288
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