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Human neuronal threonine-for-leucine-248 α7 mutant nicotinic acetylcholine receptors are highly Ca(2+) permeable
A cDNA coding for the human neuronal nicotinic α7 receptor subunit with Leu-248 mutated to threonine was expressed in Xenopus oocytes. When activated by acetylcholine (AcCho), the receptors expressed generated currents that had low desensitization, linear current–voltage relation, and high apparent...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16293/ https://ncbi.nlm.nih.gov/pubmed/10716716 |
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