Human neuronal threonine-for-leucine-248 α7 mutant nicotinic acetylcholine receptors are highly Ca(2+) permeable

A cDNA coding for the human neuronal nicotinic α7 receptor subunit with Leu-248 mutated to threonine was expressed in Xenopus oocytes. When activated by acetylcholine (AcCho), the receptors expressed generated currents that had low desensitization, linear current–voltage relation, and high apparent...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Fucile, S., Palma, E., Mileo, A. M., Miledi, R., Eusebi, F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050582497
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