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Modulation of nicotinic acetylcholine receptors by strychnine

Strychnine, a potent and selective antagonist at glycine receptors, was found to inhibit muscle (α(1)β(1)γδ, α(1)β(1)γ, and α(1)β(1)δ) and neuronal (α(2)β(2) and α(2)β(4)) nicotinic acetylcholine receptors (AcChoRs) expressed in Xenopus oocytes. Strychnine alone (up to 500 μM) did not elicit membran...

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Detalhes bibliográficos
Main Authors: García-Colunga, Jesús, Miledi, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22429/
https://ncbi.nlm.nih.gov/pubmed/10097172
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