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Modulation of nicotinic acetylcholine receptors by strychnine

Strychnine, a potent and selective antagonist at glycine receptors, was found to inhibit muscle (α(1)β(1)γδ, α(1)β(1)γ, and α(1)β(1)δ) and neuronal (α(2)β(2) and α(2)β(4)) nicotinic acetylcholine receptors (AcChoRs) expressed in Xenopus oocytes. Strychnine alone (up to 500 μM) did not elicit membran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: García-Colunga, Jesús, Miledi, Ricardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC22429/
https://ncbi.nlm.nih.gov/pubmed/10097172
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