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Modulation of nicotinic acetylcholine receptors by strychnine

Strychnine, a potent and selective antagonist at glycine receptors, was found to inhibit muscle (α(1)β(1)γδ, α(1)β(1)γ, and α(1)β(1)δ) and neuronal (α(2)β(2) and α(2)β(4)) nicotinic acetylcholine receptors (AcChoRs) expressed in Xenopus oocytes. Strychnine alone (up to 500 μM) did not elicit membran...

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Autores principales: García-Colunga, Jesús, Miledi, Ricardo
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC22429/
https://ncbi.nlm.nih.gov/pubmed/10097172
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