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Blockage of 5HT(2C) serotonin receptors by fluoxetine (Prozac)

Fluoxetine (Prozac) inhibited the membrane currents elicited by serotonin (5-hydroxytryptamine; 5HT) in Xenopus oocytes expressing either cloned 5HT(2C) receptors or 5HT receptors encoded by rat cortex mRNA. Responses of 5HT(2C) receptors, elicited by nM concentrations of 5HT, were rapidly and rever...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ni, Y. G., Miledi, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20038/
https://ncbi.nlm.nih.gov/pubmed/9050900
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