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Blockage of 5HT(2C) serotonin receptors by fluoxetine (Prozac)

Fluoxetine (Prozac) inhibited the membrane currents elicited by serotonin (5-hydroxytryptamine; 5HT) in Xenopus oocytes expressing either cloned 5HT(2C) receptors or 5HT receptors encoded by rat cortex mRNA. Responses of 5HT(2C) receptors, elicited by nM concentrations of 5HT, were rapidly and rever...

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Autori principali: Ni, Y. G., Miledi, R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20038/
https://ncbi.nlm.nih.gov/pubmed/9050900
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