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Human neuronal threonine-for-leucine-248 α7 mutant nicotinic acetylcholine receptors are highly Ca(2+) permeable

A cDNA coding for the human neuronal nicotinic α7 receptor subunit with Leu-248 mutated to threonine was expressed in Xenopus oocytes. When activated by acetylcholine (AcCho), the receptors expressed generated currents that had low desensitization, linear current–voltage relation, and high apparent...

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Bibliografski detalji
Glavni autori: Fucile, S., Palma, E., Mileo, A. M., Miledi, R., Eusebi, F.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC16293/
https://ncbi.nlm.nih.gov/pubmed/10716716
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