Loading...

Threonine-for-leucine mutation within domain M2 of the neuronal alpha(7) nicotinic receptor converts 5-hydroxytryptamine from antagonist to agonist.

A study was made of the effects of 5-hydroxytryptamine (5HT) on homomeric neuronal nicotinic receptors (nAcChoR) expressed in Xenopus oocytes after injection of cDNA encoding the wild-type chicken alpha(7) subunit. Acetylcholine (AcCho) elicited large currents (IAcCho) that were reduced by 5HT in a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Palma, E, Mileo, A M, Eusebi, F, Miledi, R
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38313/
https://ncbi.nlm.nih.gov/pubmed/8855338
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!