Threonine-for-leucine mutation within domain M2 of the neuronal alpha(7) nicotinic receptor converts 5-hydroxytryptamine from antagonist to agonist.

Ítems similars

• Neuronal nicotinic threonine-for-leucine 247 α(7 )mutant receptors show different gating kinetics when activated by acetylcholine or by the noncompetitive agonist 5-hydroxytryptamine
  per: Palma, E., et al.
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• Human neuronal threonine-for-leucine-248 α7 mutant nicotinic acetylcholine receptors are highly Ca(2+) permeable
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• Strychnine activates neuronal α7 nicotinic receptors after mutations in the leucine ring and transmitter binding site domains
  per: Palma, Eleonora, et al.
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  per: Palma, Eleonora, et al.
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• Effects of Zn(2+) on wild and mutant neuronal α(7) nicotinic receptors
  per: Palma, E., et al.
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