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Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1.

We have analyzed recombinant human immunodeficiency virus type 1 reverse transcriptases that contain mutations at position 184. These variants retain high levels of RNA-dependent DNA polymerase activity and show resistance to ddITP. However, the mutants varied in their ability to polymerize processi...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Boyer, P L, Hughes, S H
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162796/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492119/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1624
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