Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1.

We have analyzed recombinant human immunodeficiency virus type 1 reverse transcriptases that contain mutations at position 184. These variants retain high levels of RNA-dependent DNA polymerase activity and show resistance to ddITP. However, the mutants varied in their ability to polymerize processi...

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Bibliographic Details
Main Authors: Boyer, P L, Hughes, S H
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC162796/
https://ncbi.nlm.nih.gov/pubmed/7492119
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