Antiviral effect in human cytomegalovirus-infected cells, pharmacokinetics, and intravitreal toxicology in rabbits of acyclovir diphosphate dimyristoylglycerol.

Acyclovir diphosphate dimyristoylglycerol (ACVDP-DG) is a lipid prodrug which is active against ACV-resistant strains of herpes simplex virus because of its intracellular metabolism to ACV monophosphate. In human cytomegalovirus (HCMV)-infected MRC-5 cells, ACVDP-DG was ninefold more active than ACV...

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書誌詳細
出版年:	Antimicrob Agents Chemother
主要な著者:	Shakiba, S, Freeman, W R, Flores-Aguilar, M, Munguia, D, Tatebayashi, M, Besen, G, Amani, R, Wiley, C A, Vuong, C, Aldern, K A
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1995
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574537/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1383
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

Antiviral effect in human cytomegalovirus-infected cells, pharmacokinetics, and intravitreal toxicology in rabbits of acyclovir diphosphate dimyristoylglycerol.

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